The Ordinary's portfolio of Vitamin C includes the following formulations: Vitamin C Suspension 30% in Silicone Vitamin C Suspension 23% + HA Spheres 2% Ascorbyl Glucoside Solution 12% Ascorbyl Tetraisopalmitate Solution 20% in Vitamin F Magnesium Ascorbyl Phosphate 10% Ascorbic Acid 8% + Alpha Arbutin 2% Ethylated Ascorbic Acid 15% Solution 100% L-Ascorbic Acid Powder Topical Vitamin C offers a wide array of benefits to the skin. EWG’s Skin Deep rates thousands of personal care product ingredients, culled from ingredient labels on products, based on hazard information pulled from the scientific literature and industry, academic and regulatory databases.

White, in Abeloff's Clinical Oncology (Sixth Edition), 2020 Laetrile. Laetrile, also known as amygdalin, is a cyanogenic glucoside found in the pits of many fruits, in raw nuts, and in other plants such as lima beans, clover, and sorghum. 28,29 Although it is frequently called vitamin B 17 in the lay literature, amygdalin is not recognized as a vitamin by the Committee on. Coco Glucoside is an non-ionic surfactant that can be used as a foaming, cleansing, conditioning, and thickening agent to liquid cleansers and shampoos.

Generic Name: ferrous gluconate (FER us GLOO koe nate)
Brand Name:Ferate, Fergon, Ferralet, Simron
Dosage Forms: oral tablet (240 mg; 256 mg; 324 mg; 324 mg (37.5 mg elemental iron); 325 mg)

What is ferrous gluconate?

Ferrous gluconate is a type of iron. You normally get iron from the foods you eat. In your body, iron becomes a part of your hemoglobin (HEEM o glo bin) and myoglobin (MY o glo bin). Hemoglobin carries oxygen through your blood to tissues and organs. Myoglobin helps your muscle cells store oxygen.

Ferrous gluconate is used to treat or prevent iron deficiency anemia (a lack of red blood cells caused by having too little iron in the body).

Ferrous gluconate may also be used for purposes not listed in this medication guide.

Warnings

You should not use ferrous gluconate if you have hemochromatosis, hemosiderosis, or hemolytic anemia.

Before taking this medicine

You should not use ferrous gluconate if you are allergic to it, or if you have:

• iron overload disorder (hemochromatosis, hemosiderosis); or

• hemolytic anemia (caused by the breakdown of red blood cells).

To make sure ferrous gluconate is safe for you, tell your doctor if you have ever had:

• ulcerative colitis;

• stomach ulcers or similar stomach problems;

• thalassemia (a genetic disorder of red blood cells); or

• if you receive regular blood transfusions.

Ask a doctor before using this medicine if you are pregnant or breast-feeding. Your dose needs may be different during pregnancy or while you are nursing.

Ferrous gluconate is not approved for use by anyone younger than 18 years old.

How should I take ferrous gluconate?

Use this medication exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended.

Take ferrous gluconate on an empty stomach, at least 1 hour before or 2 hours after a meal.

Ferrous gluconate may be taken with food if it upsets your stomach.

Take ferrous gluconate with a full glass of water or juice.

Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not crush, chew, or break an extended-release tablet. Swallow the pill whole.

Ferrous gluconate can stain your teeth, but this effect is temporary. To prevent tooth staining, mix the liquid form of ferrous gluconate with water or fruit juice (not with milk) and drink the mixture through a straw. You may also clean your teeth with baking soda once per week to treat any tooth staining.

Ferrous gluconate may be only part of a complete program of treatment that also includes a special diet. Follow the diet plan created for you by your doctor or nutrition counselor. Get familiar with the list of foods you should eat to make sure you get enough iron in your diet.

Store at room temperature, away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if you think you have used too much of ferrous gluconate, or if a child has accidentally swallowed it. An overdose of ferrous gluconate can be fatal to a child.

Overdose symptoms may include drowsiness, severe nausea or stomach pain, vomiting, bloody diarrhea, coughing up blood or vomit that looks like coffee grounds, shallow breathing, weak and rapid pulse, cold or clammy skin, blue lips, and seizure (convulsions).

What should I avoid while taking ferrous gluconate?

Ask your doctor before using any vitamin or mineral supplement, or an antacid. Use only the type of antacid or supplements that your doctor recommends. Some minerals or antacids can make it harder for your body to absorb ferrous gluconate.

Avoid taking antacids or antibiotics within 2 hours before or 2 hours after taking ferrous gluconate. This is especially important if you take:

• ciprofloxacin, levofloxacin, lomefloxacin, norfloxacin, ofloxacin; or

• demeclocycline, doxycycline, minocycline, or tetracycline.

Certain foods can also make it harder for your body to absorb ferrous gluconate. Avoid taking this medicine within 1 hour before or 2 hours after eating fish, meat, liver, and whole grain or 'fortified' breads or cereals.

Ferrous gluconate side effects

Get emergency medical help if you have signs of an allergic reaction:hives, blistering or peeling skin; fever; difficulty breathing; swelling of your face, lips, tongue, or throat.

Glucoside 5mg

Call your doctor at once if you have:

• bright red blood in your stools;

• black or tarry stools;

• a fever;

• stomach pain;

• coughing up blood or vomit that looks like coffee grounds; or

• pain in your chest or throat when swallowing a ferrous gluconate tablet.

Common side effects may include:

• constipation, diarrhea;

• nausea, vomiting, stomach pain;

• loss of appetite;

• green-colored stools; or

• temporary staining of the teeth.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Ferrous gluconate dosing information

Usual Adult Dose for Iron Deficiency Anemia:

Initial dose: 960 mg/day ferrous gluconate (120 mg/day elemental iron) for 3 months
-Give in divided doses (1 to 3 times daily)

Usual Adult Dose for Vitamin/Mineral Supplementation:

Initial dose: 1 tablet orally three to four times a day
or
Initial dose: 48 to 144 mg/day ferrous gluconate (6 to 18 mg/day elemental iron) orally, in divided doses (1 to 3 times daily)
51 and over: 40 to 64 mg/day ferrous gluconate (5 to 8 mg/day elemental) orally, in divided doses (1 to 3 times daily)

Usual Adult Dose for Anemia Associated with Chronic Renal Failure:

Initial dose: 1600 mg/day ferrous gluconate (200 mg/day elemental iron) orally in divided doses (1 to 3 times daily)
Comments:
-If goals are not met with oral iron after 1 to 3 months, consider IV iron supplementation.
-Smaller daily doses may be better tolerated

Usual Pediatric Dose for Iron Deficiency Anemia:

0 to 5 years: 24 to 48 mg/kg/day ferrous gluconate (3 to 6 mg/kg/day elemental iron)
5 to 12 years: 480 mg ferrous gluconate (60 mg/day elemental)
12 to 18 years male: 480 mg ferrous gluconate (60 mg elemental) orally daily
12 to 18 years female: 480 to 960 mg/day ferrous gluconate (60 to 120 mg/day elemental)
-Give in divided doses (1 to 3 times daily)

Usual Pediatric Dose for Vitamin/Mineral Supplementation:

Preterm infant (less than 37 weeks gestation), 0 to 12 months: 16 mg/kg/day ferrous gluconate (2 mg/kg/day elemental iron)
0 to 6 months: 1.6 to 2.16 mg/day ferrous gluconate (0.2 to 0.27 mg/day elemental)
7 to 12 months: 56 to 88 mg/day ferrous gluconate (7 to 11 mg/day elemental)
1 to 3 years: 32 to 72 mg/day ferrous gluconate (4 to 9 mg/day elemental)
4 to 8 years: 32 to 80 mg/day ferrous gluconate (4 to 10 mg/day elemental)
9 to 13 years: 48 to 64 mg/day ferrous gluconate (6 to 8 mg/day elemental)
14 to 18 years: 64 to 120 mg/day ferrous gluconate (8 to 15 mg/day elemental)
-Give in divided doses (1 to 3 times daily)

What other drugs will affect ferrous gluconate?

Other drugs may interact with ferrous gluconate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

More about ferrous gluconate

Consumer resources

Other brands

Fergon, Ferate

Professional resources

Related treatment guides

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Glucoside Definition

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Copyright 1996-2021 Cerner Multum, Inc. Version: 2.01.

What could be sweeter than surfactants made out of sugar?

Alkyl Polyglucosides are a key part of any cosmetic chemists ingredient arsenal and it’s for good reason. These little babies have many pleasing attributes including but not limited to:

• Their ability to act as solubilisers or emulsifiers in products.
• Their mildness as surfactants (although this does vary from product to product)
• Their wetting ability
• Their natural-ness (renewable resources rather than petrochemical based)
• The fact that they are allowed in organic formulations
• Their high foaming properties
• Their biodegradability
• Their cost efficiency

They also have pleasant, not-too-chemical sounding names:

• Decyl Glucoside
• Caprylyl/Capryl Glucoside
• Lauryl Glucoside
• Coco Glucoside

Not that names bothers me too much but I reluctantly accept that fact that clean labelling is a ‘thing’……

Glucoside Mr

So what is there to gossip about?

Glucoside Medication

Well, while there is nothing too scandalous about these sweet little things there are a few minor details that you should be aware of before merrily skipping off, hand in hand with one of the above thinking that life will be as easy as pie. Here are some of those things.

1. Check their palm status. There are two types of feedstock that go into a sugar surfactant – sugar (usually from starch which comes from corn) and fatty alcohol which comes from a fat which could be animal, vegetable or petrochemical. In reality, at this moment in time the fatty alcohol is pretty much always from palm. If you are a palm free or palm conscious brand you need to be aware of this. Luckily the big soapers that make glucosides are all involved in the Round Table for Sustainable Palm but that doesn’t necessarily mean that the manufacturers values will align with yours.
2. Every maufacturer produces a glucoside that’s chemistry is slightly different! There are a few companies making these sugar based surfactants now and each one produces a slightly different version of each of the above. It is important to understand that the glucoside family of surfactants are polymeric and as such the name gives you a relative rather than an absolute structure. Basically that means that you can buy Decyl Glucoside from three factories and receive three surfactants that perform differently in your formulation from each other.Often this isn’t a big issue but if you are using the glucoside as a solubiliser the degree of polymerisation (or the glucoside part) can have a huge impact on the solubilising power of the sugar surfactant. An example of this would be in a spritzer. You might have a spritzer that is being solubilised by Decyl glucoside, you change supplier for your Decyl Glucoside and find that you are now having to use twice as much solubiliser as before OR in a worst case scenario it doesn’t work at all. This sort of thing is usually less of an issue in a shampoo or body wash although it could account for some cloudiness or viscosity changes between suppliers.
3. While the INCI names are different this range of surfactants all work in the same way and cross over to some degree. In many personal care (and some cleaning applications) we are not looking for the ‘precise and accurate’ functionality from our surfactants that we might need when making products for food, pharmaceutical or animal health. Because us personal care types are more generalists in that way there is often very little benefit to be had in blending two or three different non-ionics together in a formula. The range of glucosides listed above all work by emulsifying dirt from the surface of the hair, skin or benchtop. Also they are all based on alcohols ranging from C8-C16 with all except the Caprylyl/ Capryl Glucoside containing broad cuts of all of the above alcohols (caprylyl/ capryl glucoside is a C8-C10 and is the shortest chain length glucoside used regularly). So pick one for your cleansing formula then look at other technologies to give you some complimentary features.
4. While the range may all work the same they do vary in ‘mildness’. Decyl and Coco glucoside are the two mildest glucosides available for cleansing formulations. The Lauryl Glucoside is slightly more irritating but not that bad but the caprylyl/ capryl glucoside is quite a bit harsher on the skin. That said all are relatively mild and can be safely formulated into a baby product or products for those with sensitive skin.
5. The activity levels of the surfactants change from grade to grade and manufacturer to manufacturer. As with all surfactants it is really important to check on just how active the surfactant is before diving in and using it. Glucosides are usually pretty high up there in terms of solids content with concentrations anywhere between 50% active and 75% active common. This is in contrast to many anionic and amphoteric surfactants which, when sold as liquids are often sold as 25-30% solutions. A quick check of the MSDS will give you the data you need to work out an appropriate addition percentage.
6. Glucosides can turn solid in winter! The Glucoside barometer is almost as reliable as the coconut oil barometer in my laboratory. Autumn and Winter see my Decyl Glucoside turned into a solid, gritty white mess while late spring and summer tend to turn it into a thin, free-flowing fluid. This fate is shared to one degree or another across the board with only the short chain Caprylyl/ Capryl Glucoside still pourable at temps under 15C – that said it can get mighty thick due to its high active level! Gentle heating and good mixing is all that is needed in winter to put them right – don’t forget to mix or else you will end up with a dose of surfactant that is more or less active than you planned for!
7. These guys typically have a high pH. While it is not unusual for surfactants to have pH values in their ‘as supplied’ form up around the 9’s glucosides can often have pH values between 11-12. This is pretty high and will require adjusting for in many cosmetic formulations. Shampoos, body washes and facial cleansers can have their pH adjusted down with citric acid. If you are using or planning to use glucosides in your formula do have your pH meter handy (and learn how to use it).
8. Glucosides are actually pretty horrible to use in the hair. OK so I see shampoo formulations with glucosides all of the time, not all of them bad but in general glucoside surfactants are not that great for the hair. This isn’t something I’ve made up or say just because I’m being picky the manufacturers of glucoside technology pointed this out way back when – google an article called ‘skin care forum’ from 1995 by Henkel! That said Henkel do mention that the glucosides do have value in products for fine hair as they do ‘ decrease wet combability and increase friction’. I think that’s a polite way of saying they knot the hair and leave it hard to brush but ‘extra volume’ is a more positive spin!
9. Glucosides are not new technology. It is often thought that these little babies are new and exciting but the truth is they were first talked about back in 1893 and have been tweaked, invested in and developed ever since. I don’t think that is a bad thing, indeed it is quite the opposite as we now have much better data on their biodegradability, irritancy potential, features and benefits. I wouldn’t be at all surprised if glucoside technology continues to be a focus of investment and would be excited to see new glucosides that harvest their fatty acids from waste material and grow the glucose from recycled paper. We’ve got to leave the fields for food or forest in my humble opinion.
10. And last of all Glucosides are great surfactants to put into an emulsion. Many of us have used the emulsifier – cetearyl alcohol and cetearyl glucoside, probably without realising that it too is a cousin of the bubbly glucosides we wash our bodies with. But beyond that we can use these non-ionic sugar surfactants to help turn our moisturisers into creamy cleansers! A little bit of coco glucoside or equivalent is far less likely to stress an emulsion than sodium lauryl sarcosinate, produces lovely creamy bubbles and is relatively mild to the skin and has a low eye irritation potential.

Well I do hope that you have enjoyed my meander into the secret life of glucosides. If you want a bit more info on their safety I suggest you check this out.

Happy mixing, reading, buying or trying.

Glucoside Medication Diabetes Side Effects

Amanda x